Date: 31 Oct 2014
Sema 3A is involved in the guidance of axons during nervous system development and induces the reorganization of actin filaments in the growth cones through the downstream protein CRMP1. Here the authors study the details of the molecular interaction between CRMP1 and the actin-binding protein Filamin-A in C. elegans.
Yoshio Goshima, M.D. & Ph.D. Professor,
Fumio Nakamura, Associate Professor, Department of Molecular Pharmacology & Neurobiology,
Graduate School of Medicine,Yokohama City University