YOKOHAMA CITY UNIVERSITY

YCU Science Summer Program 2014

In 2014, the program was organized by Graduate School of Medical Life Science, and twelve students from five cooperating universities in China, Singapore, Taiwan, Malaysia, and USA joined in this program.

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Practical Class No.2: Data-mining of metabolomic information obtained by NMR

Prof. Jun Kikuchi gave a workshop on matabolomics analysis of urine samples form patients, showing how mathematical tools can be used to look at correlations between the different small molecule analytes present, and use these as markers for disease. The mathematics was quite a challenge!









Lecture No.5: Exploring invisible states of proteins by NMR spectroscopy

Prof. Hideo Takahashi explained the ability of modern NMR machines to look inside protein molecules and detect their motions. Almost all proteins have a defined shape in solution, but also vibrate substantially, and these motions are essential to their function. NMR is an ideal technique to understand how proteins move, and how these motions change when they bind partner molecules in the cell.








Lecture No.6: Can we build medical nanorobots from biological machines?

Dr. Jonathan Heddle talked about the dream of building armies of minute robots that can enter our bodies and cure diseases by simply repairing our bodies on a molecular level.

















The science fiction doesn’t quite match reality, but we are getting closer to designing DNA and protein molecules that make shapes we want in 2 and 3 dimensions. Progress has been very rapid over the last few years, and protein designs are now entering the main-stream in manufacturing processes as well as medical applications.

Lecture No.7: Plant cells – the green factories of the future

Dr. Jenny Mortimer spoke about genetic engineering and its promise of more, and more nutritional food stuffs.












She also talked about biofuels, and how engineering the sugar component of plants may allow us to create readily digestible plant cell walls, allowing them to be converted quickly and cheaply into new fuel sources.

Special Facility Tour

Asso Prof. Satoko Akashi showed the students Mass Spectrometer and explained about the structural analysis of proteins.












With her explanation, they were looking carefully at the inside of the spectrometer with interests.

LINKS

DAY 1
(August 19th)


DAY 2
(August 20th)


DAY 3
(August 21th)


DAY 4
(August 22th)


DAY 5
(August 23th)


Voices of Participants

Voices of Lecturers